Does Angiotensin II Increase Glomerular Filtration Rate
“Angiotensin II causes increase in glomerular filtration rate”
Summary
Angiotensin II preferentially constricts the efferent arteriole, which raises glomerular capillary pressure and typically increases or maintains GFR, especially during reduced renal perfusion. At very high concentrations it can lower GFR, but under normal physiological conditions the peptide tends to cause a net increase in GFR.
Sources 59 searched
- Regulation of glomerular filtration rate and sodium excretion by angiotensin II - PubMed
Angiotensin II (AngII) helps to prevent excessive decreases in GFR in different physiological and pathophysiological conditions by preferentially constricting the efferent arterioles, an action that can be mediated by either intrarenally formed ...
- Control of glomerular filtration rate by circulating angiotensin II - PubMed
Replacement of circulating ANG II during SQ 14225 infusion, by intravenous infusion of ANG II at rates that decreased RBF to control levels, increased GFR, FF, and RE to levels not significantly different from control while RAP was maintained ...
- Effect of exogenous and endogenous angiotensin II on intrarenal distribution of glomerular filtration rate in rats - PubMed
Different changes in glomerular ... Angiotensin II (AngII) has been implicated in such changes, but the experimental evidence has been conflicting, probably because o …...
- Angiotensin II - an overview | ScienceDirect Topics
The net effect is elevation of the hydraulic pressure in the glomerular capillary (PGC), which tends to maintain the GFR even under conditions of renal hypoperfusion. In contrast, at higher concentrations, angiotensin II can lower GFR by lowering the surface area available for filtration and by ...
- Glomerular actions of angiotensin II - ScienceDirect
Angiotensin II regulates whole kidney glomerular filtration rate by influencing one or more of the determinants of single nephron glomerular filtration rate, particularly the ultrafiltration coefficient and glomerular plasma flow rate.
- Angiotensin II increases glomerular permeability by β-arrestin mediated nephrin endocytosis | Scientific Reports
Angiotensin II increases glomerular permeability by β-arrestin mediated nephrin endocytosis. Sci. Rep. 6, 39513; doi: 10.1038/srep39513 (2016). Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published ...
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