Are Statins Safe to Take

benefit increases the longer the statin is taken. In general, taking a statin can cut a person’s risk of ... Serious risks are rare.

Checking your browser before accessing pmc.ncbi.nlm.nih.gov · Click here if you are not automatically redirected after 5 seconds

You should not take statins if you are pregnant or breastfeeding. They are also not recommended for people who have certain types of liver disease. To safely take statins, you should: Take your statin as prescribed. You should not stop taking this medicine on your own, since that can lead to a serious problem or, in rare cases, even cause death.

The University of Oxford’s Cholesterol Treatment Trialists’ Collaboration found that taking a statin did not cause a statistically significant excess increase in memory loss, depression, sleep disturbance, erectile dysfunction, weight gain, nausea, fatigue, and headache, when compared with ...

The findings for urinary composition alteration and oedema are of uncertain clinical importance, given that the absence of a dose-response in the more intensive versus less intensive statin trials does not support a cause-and-effect relationship. Our post-hoc analyses indicate that although statin therapy might marginally increase urinary protein concentrations, there was no significant impact on any other renal outcomes (including acute kidney injury). This result is in line with findings from the Study of Heart and Renal Protection,68 which showed no significant effect of simvastatin plus ez

Statins reduce cardiovascular mortality and morbidity as well as cardiovascular events in patients with a very high risk of cardiovascular disease (CVD) and also in subjects with high or moderate risk by reducing the levels of low-density lipoprotein cholesterol (LDL-C). Although they are considered to be drugs with a very good safety profile, because of their wide use there are many concerns that their adverse effects might compromise their proven beneficial effects. Therefore this article reviews all the data and provides an evidence- based insight what are the proven adverse effects of statins and what are the "myths" about them. The most important side effects include myopathy and rhabdomyolysis.

These side effects reverse once you stop taking the medicines. There is limited evidence to prove a cause-effect relationship, and several studies have found that statins have no effect on memory.

Most statin side effects listed on drug packaging are not supported by strong evidence, a new review suggests. Of 66 potential side effects, researchers identified only 4 linked to statins.

Cholesterol-lowering statin drugs do not cause most of the side effects attributed to them on package inserts, a large analysis of past clinical trials found.