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Summary
Prions are misfolded proteins that cause neurodegenerative disorders such as Creutzfeldt‑Jakob disease and bovine spongiform encephalopathy, leading to brain damage. The description on the cited page matches current medical understanding from health authorities and scientific literature, and no contradictory evidence was found.
Sources 57 searched
- About Prion Diseases | Prions | CDC
Prion diseases occur when proteins in the body misfold and cause brain damage and other symptoms.
- Borna Disease Virus and the Brain - PMC
Borna disease virus causes CNS disease in a broad range of vertebrate animal species that is manifested by behavioral abnormalities and diverse pathology. BDV provides an important paradigm for the investigation of the mechanisms and consequences of viral persistence in the CNS. Studies on this viral system will contribute to the elucidation of immune-mediated pathological events involved in virally induced neurological disease, as well as the mechanisms whereby viruses induce neurobehavioral disturbances in the absence of the hallmarks of cytolysis and inflammation.
- The global burden of neurological disorders: translating evidence into policy - PMC
It is measured by taking the prevalence of the condition multiplied by the disability weight (the severity of health loss associated with a health state that is developed through surveys of the general public) for that condition. Risk factors are potentially modifiable causes of neurological disorders.
- Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 - PMC
The four largest contributors of neurological DALYs were stroke (42·2% [38·6–46·1]), migraine (16·3% [11·7–20·8]), Alzheimer's and other dementias (10·4% [9·0–12·1]), and meningitis (7·9% [6·6–10·4]). For the combined neurological disorders, age-standardised DALY rates were ...
- Brain Diseases | MedlinePlus
In some cases, damage is permanent. In other cases, treatments such as surgery, medicines, or therapies such as physical, occupational, and speech therapies, may cure the disease or improve the symptoms. Brain Basics: Know Your Brain (National Institute of Neurological Disorders and Stroke)
- Prevalence of the major neurological disorders in a semi-urban community in northern Benin - ScienceDirect
No case of dementia or Parkinson's disease was found. Socio-demographic factors associated with these conditions were as follows: tension-type headaches: age (p = .020); peripheral neuropathies: age (p = 0. 000); sex (p = .006); profession (p = .004); marital status (p = .032); and level of education (p = .003); stroke: age (p = .000) and marital status (p = .000). These results point to a high prevalence of neurological disorders in Titirou
- Creutzfeldt-Jakob disease: Rare cause of dementia-Creutzfeldt-Jakob disease - Symptoms & causes - Mayo Clinic
Creutzfeldt-Jakob disease and related conditions appear to be caused by changes to a type of protein called a prion. These proteins are typically produced in the body. But when they encounter infectious prions, they fold and become another shape that's not typical.
- كيفية تضاعف البريونات (مايو كلينك)
Prions are proteins that occur naturally in the brains of animals and people. Normally, the proteins are harmless, but when they're misshapen, they can cause devastating illnesses such as BSE disease in cattle and Creutzfeldt-Jakob disease in humans · There is a problem with information submitted ...
- Prions (infectious proteins) - Faculty of Medicine - University of Kufa
The abnormally folded, filamentous structure is thought to be caused by genetic changes in this protein as a result of exposure to various internal and external stimuli. Its distinguishing feature is that it lacks distinct or identifiable DNA and causes significant and dangerous diseases known as slow or long-term disorders, such as.