1947 Report on Sedative in Plant Oleoresin Fraction Fact-Checked
“The presence of the potent sedative principle within the "oleoresin fraction" of the plant was formally reported in 1947 by researchers investigating the crude extracts. 1”
Summary
No current sources confirm that a potent sedative principle in the oleoresin fraction of a plant was formally reported in 1947. The available literature discusses sedative compounds and oleoresins, but none document a 1947 report of such a finding.
Sources 59 searched
- Sedatives
During both World War I and World War II, valerian was used to treat shell-shocked troops and calm civilians from the psychological nervous effects of air raids. Valerian root has been mixed with other botanicals such as hops and kava-kava as a sedative to induce potent, hypnotic sleep.
- C h a p t e r 2 Medicinal plant development in the United States Steven Foster
There are a number of studies that show antispasmodic and sedative action for
- Oleoresins - an overview | ScienceDirect Topics
In subject area: Agricultural and Biological Sciences · Oleoresin is defined as a complex mixture of terpenoids that includes a turpentine fraction (monoterpenes and sesquiterpenes) and a rosin fraction (diterpenes), which functions to discourage insect predation and seal wounds in plants ...
- Inventing a herbal tradition: The complex roots of the current popularity of Epilobium angustifolium in Eastern Europe - ScienceDirect
In Lithuania one middle-aged woman claimed she (and her mother) used fermented flowers to treat the prostate problems of her relatives. Another female respondent said that E. angustifolium should induce relaxation and sedation, while her husband and her son did not feel such an effect. A Lithuanian-speaking woman in Belarus reported using the plant against inflammation two years ago.
- Sedative and hypnotic effects of Iranian traditional medicinal herbs used for treatment of insomnia - PMC
Nevertheless, Noguerira and Vassilieff studied the hypnotic effect of the other geniuses of Rosaceae family, that is, Rubus brasiliensis and suggested that a benzodiazepine-like principle in hexanic fraction of this herb induced the hypnotic effect through GABAa system (Nogueira and Vassilieff, ...
- The Essential Oil Composition and Antimicrobial Activity of Liquidambar formosana Oleoresin - PMC
The oleoresin essential oils of Liquidambar formosana have potential therapeutic benefits. However, current research on L. formosana oleoresin essential oil is still in its early stages, and its chemotypic characterization is undefined. For better leveraging of plant resources and application of the essential oil, we collected 25 L.
- Introduction - NTP Technical Report on the Toxicity Studies of Myristicin (CASRN 607-91-0) Administered by Gavage to F344/NTac Rats and B6C3F1/N Mice - NCBI Bookshelf
Acute administration of nutmeg essential oil (0.5 mL/cage) to mice by inhalation resulted in inhibition of locomotion, and disruption of rope-climbing and bar-pressing activities.11,43 Rats and guinea pigs dosed with myristicin (5 to 20 mg/kg intraperitoneal injection) were hyperactive for the first 30 minutes after exposure and then become sedated and nonresponsive for up to 2 hours.30 Myristicin may promote anxiolytic behavior in male Sprague Dawley rats dosed with midazolam.44 A mouse tetrad study, characterizing the effect of nutmeg extract on locomotor activity, catalepsy, body temperatur
- Pharmacological exploration of the sedative mechanism of hesperidin identified as the active principle of Citrus sinensis flowers - PubMed
The methanol and dichloromethane ... 129.15+/-21.25 mg/kg, respectively. Hesperidin (ED50=11.34+/-2.48 mg/kg) was identified in the methanol extract as the sedative active principle of this plant....
- Toxicological and Sedative Effects of Chipilin (Crotalaria longirostrata) Leaf Extracts Obtained by Maceration and Supercritical Fluid Extraction | ACS Omega
The present results showed that the Chipilin oleoresin has a sedative effect without causing toxic effects since after exposure to the light stimulus (stage III) its behavior was similar to that of the control.
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