This tool is donation based and free. 🙏 We're looking for donations to keep it running — $360/year covers our server costs.

$18 of $360 · 5%
Donate

Mitochondria produce ATP via respiration – True

Question asked:

“Mitochondria produce cellular energy (ATP) via respiration”
True
Confidence: High Checked on September 24, 2026

Summary

Mitochondria generate cellular energy by converting nutrients into ATP through the process of aerobic respiration, specifically oxidative phosphorylation in the electron transport chain. This fundamental role in cellular metabolism is well established in current biological literature.

Sources 59 searched

ncbi.nlm.nih.gov
genome.gov
  • Mitochondria

    That energy is produced by having chemicals within the cell go through pathways, in other words, be converted. And the process of that conversion produces energy in the form of ATP, because the phosphate is a high-energy bond and provides energy ...

nature.com
pmc.ncbi.nlm.nih.gov
  • Real-time assessment of relative mitochondrial ATP synthesis response against inhibiting and stimulating substrates (MitoRAISE) - PMC

    MDA-MB-231, ZR-75–1, HeLa, BT-20, and HCC1428 cells showed a negative or no correlation between Total ATP level and GM-induced and S-induced ASR (Fig. 3b). Previous studies have indicated that MCF7 and BT-474 cells demonstrate metabolic profiles characterized by relatively high mitochondrial respiration and low glycolysis, whereas MDA-MB-231 and BT-20 cells exhibit metabolic profiles characterized by high glycolysis and low mitochondrial respiration [18]. These data suggest that the observed variances are likely to be influenced more by the cellular metabolism status than by batch effects.

  • Analysis of mitochondrial respiration and ATP synthase in frozen brain tissues - PMC

    Using small amounts of frozen tissue, we systematically analyzed the quantity as well as activity of both the electron transport chain complexes and ATP synthase in rat brains during postnatal development. We reveal a previously little-known pattern of increasing mitochondrial respiration capacity with brain development. In addition to providing proof-of-principle evidence that mitochondrial activity changes during brain development, our study details an approach that can be applicable to many other types of frozen cell or tissue samples.

  • The curious case of vanishing mitochondria - PMC - NIH

    Due to their involvement in the energy metabolism, mitochondria are essential for most eukaryotic cells. Microbial eukaryotes living in low oxygen environments possess reduced forms of mitochondria, namely mitochondrion-related organelles (MROs). These do not produce ATP by oxidative ...

sciencedirect.com
pubmed.ncbi.nlm.nih.gov
  • Mitochondria as we don't know them - PubMed

    Biochemistry textbooks depict mitochondria as oxygen-dependent organelles, but many mitochondria can produce ATP without using any oxygen. In fact, several other types of mitochondria exist and they occur in highly diverse groups of eukaryotes ...

This fact check is free and donation-based. $1 powers ~30 fact-checks.

Donate $1 to support fact-checking

Check another fact